HitPredict

Interactor 1: MXI1 (P50540)
Max-interacting protein 1 (Max interactor 1)
Gene: MXI1

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	7889570
Identification Methods	coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 228 Mm			1 1098
+	Hs
		257755 MXI1_HUMAN (1-228): 7.93e-92: 270: 96.05		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Mm
		840196 MAD1_MOUSE (7-223): 1.2e-65: 204: 55.56		SIN3B_MOUSE (1-1098): 0: 1366: 100.00
+	Mm
		139907 MNT_MOUSE (42-184): 2.45e-40: 147: 30.57		SIN3B_MOUSE (1-1098): 0: 1366: 100.00
+	Hs
		257734 MYC_HUMAN (27-150): 6.97e-38: 138: 28.03		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Rn
		61827 MYC_RAT (27-150): 9.36e-39: 141: 28.03		A6K9M6_RAT (1-280): 3.92e-95: 306: 96.79
+	Hs
		840222 MXI1_HUMAN (1-228): 7.93e-92: 270: 96.05		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Mm
		840232 MXI1_MOUSE (1-228): 4.56e-88: 261: 100.00		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Mm
		840195 MAD1_MOUSE (7-223): 1.2e-65: 204: 55.56		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Hs
		983439 MAD1_HUMAN (7-223): 4.84e-62: 195: 58.07		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Mm
		1141057 Q91VN7_MOUSE (21-217): 7.95e-56: 178: 53.03		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Dm
		1137188 X2JDM5_DROME (32-153): 1.25e-34: 132: 26.83		Q5U0Y0_DROME (134-264): 5.22e-23: 108: 41.79
+	Hs
		1302436 MAD3_HUMAN (8-193): 3.05e-49: 161: 49.47		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Ce
		60879 MXL3_CAEEL (65-167): 2.44e-20: 87.6: 25.24		SIN3_CAEEL (4-156): 7.01e-31: 134: 31.82
+	Mm
		139906 MNT_MOUSE (42-184): 2.45e-40: 147: 30.57		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Hs
		1302431 MNT_HUMAN (42-184): 1.88e-37: 139: 29.94		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Hs
		347665 MYC_HUMAN (27-150): 6.97e-38: 138: 28.03		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Hs
		898177 MAX_HUMAN (60-166): 2.04e-22: 91.4: 19.63		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49