HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 24076653
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030036 - actin cytoskeleton organization GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 191
+	Hs
		1191573 SPRE1_HUMAN (2-343): 2.84e-90: 280: 15.66		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Mm
		925824 HOME2_MOUSE (1-162): 5.14e-59: 196: 23.64		RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31
+	Mm
		892737 HOME2_MOUSE (1-162): 5.14e-59: 196: 23.64		CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00
+	Mm
		1351517 HOME2_MOUSE (1-162): 5.14e-59: 196: 23.64		RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48
+	Hs
		564611 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		1233542 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925434 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		545493 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		892483 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		925439 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		297840 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		297823 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		297827 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		297820 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		297812 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		297809 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		297819 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		297834 K0754_HUMAN (95-330): 8.97e-21: 96.6: 17.72		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82