Protein: 2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)

Gene: 2A5G, PPP2R5C
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q13362

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000775 - chromosome, centromeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

717795

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

13

20

Small-scale

0.983

High

994207

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

13

20

Small-scale

0.983

High

977480

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

5

20

High-throughput

0.932

High

718114

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

3

20

Small-scale

0.839

High

1103123

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

2

8

Small-scale

0.754

High

967705

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

17

Small-scale

0.713

High

909271

CCNG1
Cyclin-G1

4

13

Small-scale

0.694

High

951970

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

20

High-throughput

0.691

High

786587

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

17

Small-scale

0.656

High

968285

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

17

Small-scale

0.656

High

1103126

CCNG2
Cyclin-G2

3

13

Small-scale

0.656

High

354967

CHK2
Serine/threonine-protein kinase Chk2

2

6

Small-scale

0.651

High

1103127

SGO1
Shugoshin 1

3

4

Small-scale

0.650

High

1103133

FA43A
Protein FAM43A

4

4

High-throughput

0.630

High

1103141

PRR14
Proline-rich protein 14

2

3

High-throughput

0.628

High

413765

P53
Cellular tumor antigen p53

2

1

Small-scale

0.621

High

1103125

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

8

High-throughput

0.618

High

1102150

ATM
Serine-protein kinase ATM

1

1

Small-scale

0.586

High

241588

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

1103135

CIP2A
Protein CIP2A

1

1

Small-scale

0.573

High

324260

FA13A
Protein FAM13A

2

4

High-throughput

0.571

High

396044

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1103140

BAD
Bcl2-associated agonist of cell death

2

1

High-throughput

0.571

High

1067276

EP300
Histone acetyltransferase p300

1

1

Small-scale

0.561

High

251751

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

7

Small-scale

0.552

High

799070

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.552

High

703574

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.550

High

942150

WNT3A
Protein Wnt-3a

2

4

High-throughput

0.549

High

400776

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

Small-scale

0.536

High

729804

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.536

High

872293

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.536

High

971481

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

990184

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.536

High

1014089

CBX1
Chromobox protein homolog 1

1

2

High-throughput

0.536

High

1103124

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.536

High

1028182

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.530

High

858581

IEX1
Radiation-inducible immediate-early gene IEX-1

1

1

Small-scale

0.515

High

185660

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

422054

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

650735

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.493

High

1103129

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.481

High

388067

MBP
Myelin basic protein

1

0

Small-scale

0.480

High

363226

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

588611

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

695369

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

768104

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

1004520

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1103120

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1103121

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1103122

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1103139

KAT6A
Histone acetyltransferase KAT6A

1

3

Small-scale

0.479

High

1103143

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

791360

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

970444

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1103132

DZIP1
Cilium assembly protein DZIP1

1

9

Small-scale

0.457

High

181103

AXIN1
Axin-1

1

2

Small-scale

0.445

High

1103130

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

2

High-throughput

0.445

High

418101

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

1103128

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1103142

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1103131

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

3

High-throughput

0.407

High

1103134

Q8N5D4
Cyclin-G2

1

13

High-throughput

0.407

High

1103137

DNS2B
Deoxyribonuclease-2-beta

1

2

High-throughput

0.407

High

1103136

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.249

Low

1103138

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025