HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.870

The method score is based on:

Property Details
Experiments 35271311, 33961781, 21900206
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynamin_M~Dynamin_M, Dynamin_M~Dynamin_N, Dynamin_M~GED, Dynamin_M~PH, Dynamin_N~Dynamin_N, GED~GED, GED~PH, PH~PH
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 - cytoplasm
GO:0005874 - microtubule
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 870
Hs

1 864
+ Hs
+ Mm
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+ Rn
+ Hs
+ Hs
+ Hs
+ Ce
+ At
+ At
+ Hs
+ At
+ Mm
+ Sc
+ Sp
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024