HitPredict

Interactor 1: FRK (P42685)
Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)
Gene: FRK

Interactor 2: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 424
+	Hs
		440571 FYN_HUMAN (30-503): 3.54e-177: 510: 50.63		SF3B4_HUMAN (1-424): 2.4e-58: 198: 100.00
+	Hs
		362298 ABL1_HUMAN (33-495): 1.39e-159: 484: 42.03		SF3B4_HUMAN (1-424): 2.4e-58: 198: 100.00
+	Hs
		557280 SRC_HUMAN (13-503): 1.33e-178: 513: 47.89		PABP4_HUMAN (4-183): 1.21e-37: 146: 38.12
+	Hs
		550100 SRC_HUMAN (13-503): 1.33e-178: 513: 47.89		PABP1_HUMAN (4-191): 5.23e-34: 135: 36.51
+	Hs
		557468 SRC_HUMAN (13-503): 1.33e-178: 513: 47.89		PABP3_HUMAN (4-191): 1.01e-32: 132: 33.86
+	Hs
		463106 YES_HUMAN (43-503): 1.13e-173: 501: 49.25		ELAV1_HUMAN (101-322): 9.32e-15: 76.9: 17.33
+	Ce
		397842 ABL1_CAEEL (45-495): 2.23e-166: 504: 43.89		SF3B4_CAEEL (102-387): 1.69e-12: 70.3: 18.18
+	Ce
		234040 SRC2_CAEEL (21-496): 4.85e-170: 491: 50.82		SF3B4_CAEEL (102-387): 1.69e-12: 70.3: 18.18
+	Ce
		112324 SRC1_CAEEL (43-501): 7.11e-157: 458: 47.03		SF3B4_CAEEL (102-387): 1.69e-12: 70.3: 18.18