Interactor 1: TNF10 (P50591)
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)
Gene: TNFSF10

Interactor 2: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 22585859
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005164 - tumor necrosis factor receptor binding
GO:0007165 - signal transduction
GO:0008270 - zinc ion binding
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 281
Hs

1 501
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024