Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7
Interactor 2: MAT1 (P51948)
CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36)
Gene: MNAT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 26340423, 33961781, 29568061, 12527756, 33453189, 8521393, 35271311, 32707033, 36042349, 36736316, 17643375, 10801852, 9334327, 8521818, 10082552, 23602568, unassigned1655 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MAT1~Pkinase |
| Common GO terms | GO:0000439 - transcription factor TFIIH core complex GO:0005654 - nucleoplasm GO:0005675 - transcription factor TFIIH holo complex GO:0006281 - DNA repair GO:0006367 - transcription initiation at RNA polymerase II promoter and 4 others more... |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
