HitPredict

Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36042349
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 247
+	Hs
		625306 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		625296 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		841132 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		625383 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		909447 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		841174 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		960082 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		625334 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683213 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		841150 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		625130 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		646734 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683268 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646799 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683964 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		414774 CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16