HitPredict

Interactor 1: TOB1 (P50616)
Protein Tob1 (Transducer of erbB-2 1)
Gene: TOB1

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	32814053, 18377426
Identification Methods	two hybrid array, two hybrid pooling approach, tandem affinity purification, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0010468 - regulation of gene expression
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 414
+	Hs
		680430 TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00		TIA1_HUMAN (99-413): 2.4e-38: 144: 13.76
+	Hs
		516421 TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		516512 TOB2_HUMAN (1-343): 1.31e-131: 381: 55.38		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		516461 BTG2_HUMAN (1-115): 1.32e-53: 175: 41.88		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95