Interactor 1: ORC5 (P50874)
Origin recognition complex subunit 5 (Origin recognition complex 53 kDa subunit)
Gene: ORC5

Interactor 2: ORC4 (P54791)
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)
Gene: ORC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 18647841, 9001208, 17107343, 17880717, 17825065, 35217664, 22421151, 16554755, 16429126, 28191893, 37968396
Identification Methods anti bait coimmunoprecipitation, coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down, biochemical, two hybrid array, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_16~ORC4_C, ORC4_C~ORC5_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005664 - nuclear origin of replication recognition complex
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 479
Sc

1 529
+ Sc
+ Hs
+ Sc
+ Hs
+ Dm
+ Hs
+ Dm
+ At
+ Dm
+ Sp
+ At
+ Sp
+ Sp

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Last updated: 15 Jul 2024