Protein: RFC3
Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)

Gene: RFC3
Organism: Homo sapiens
Interactions: 165
UniProt ID: P40938

Gene Ontology (top 5):
GO:0000731 - DNA synthesis involved in DNA repair
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

721937

RFC4
Replication factor C subunit 4

8

16

Small-scale

0.971

High

777822

RFC5
Replication factor C subunit 5

3

16

High-throughput

0.861

High

722180

RFC1
Replication factor C subunit 1

3

20

Small-scale

0.853

High

778019

CTF18
Chromosome transmission fidelity protein 18 homolog

2

19

Small-scale

0.806

High

778023

ATAD5
ATPase family AAA domain-containing protein 5

2

20

Small-scale

0.754

High

279003

RAD17
Cell cycle checkpoint protein RAD17

5

20

Small-scale

0.721

High

778028

DCC1
Sister chromatid cohesion protein DCC1

4

7

Small-scale

0.694

High

244055

BRD4
Bromodomain-containing protein 4

4

10

Small-scale

0.692

High

777978

ORC1
Origin recognition complex subunit 1

1

7

High-throughput

0.691

High

517115

PCNA
Proliferating cell nuclear antigen

3

12

Small-scale

0.640

High

722072

RFC2
Replication factor C subunit 2

1

16

High-throughput

0.618

High

777961

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.618

High

346130

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.611

High

267486

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

2

1

High-throughput

0.606

High

778000

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

1

High-throughput

0.606

High

226740

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

552127

RFA2
Replication protein A 32 kDa subunit

2

5

High-throughput

0.584

High

650558

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

High-throughput

0.584

High

719863

RFA3
Replication protein A 14 kDa subunit

2

3

High-throughput

0.584

High

777954

CCNF
Cyclin-F

2

2

High-throughput

0.584

High

777967

H4
Histone H4

2

7

High-throughput

0.584

High

777968

H31
Histone H3.1

2

13

High-throughput

0.584

High

778044

MCM9
DNA helicase MCM9

2

4

Small-scale

0.584

High

777973

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

778043

PICK1
PRKCA-binding protein

2

1

High-throughput

0.553

High

133363

NOP56
Nucleolar protein 56

1

3

High-throughput

0.536

High

149829

RFXK
DNA-binding protein RFXANK

1

3

High-throughput

0.536

High

238259

RAD1
Cell cycle checkpoint protein RAD1

1

2

High-throughput

0.536

High

273024

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

418005

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

455174

PARP1
Poly [ADP-ribose] polymerase 1

1

11

High-throughput

0.536

High

649350

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

777970

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

777971

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

778010

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

778026

RAD9A
Cell cycle checkpoint control protein RAD9A

1

3

High-throughput

0.536

High

778031

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

778046

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.536

High

778048

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

778057

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.536

High

778051

HECD1
E3 ubiquitin-protein ligase HECTD1

2

7

Small-scale

0.533

High

777955

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

777989

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

777962

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

778014

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

1

High-throughput

0.494

High

171951

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

456396

PPBI
Intestinal-type alkaline phosphatase

1

1

High-throughput

0.489

High

777975

KLRD1
Natural killer cells antigen CD94

1

1

High-throughput

0.489

High

777987

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

778021

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.489

High

778049

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.489

High

122538

MEN1
Menin

1

3

High-throughput

0.479

High

125209

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

224338

RAD21
Double-strand-break repair protein rad21 homolog

1

4

High-throughput

0.479

High

282565

RNF8
E3 ubiquitin-protein ligase RNF8

1

3

High-throughput

0.479

High

294477

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

298239

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

302990

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

338065

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

373822

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

386238

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

391585

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

441924

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

474572

CTF8
Chromosome transmission fidelity protein 8 homolog

1

2

Small-scale

0.479

High

475442

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

569325

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

590680

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

631368

BRD2
Bromodomain-containing protein 2

1

16

High-throughput

0.479

High

707543

H2B1B
Histone H2B type 1-B

1

14

High-throughput

0.479

High

777956

NKX21
Homeobox protein Nkx-2.1

1

4

High-throughput

0.479

High

777958

CDK9
Cyclin-dependent kinase 9

1

2

High-throughput

0.479

High

777959

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.479

High

777965

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

777966

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

777972

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

777976

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

777977

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

777979

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

6

High-throughput

0.479

High

777980

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

777981

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.479

High

777982

CUL3
Cullin-3

1

4

High-throughput

0.479

High

777985

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

777986

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

777988

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.479

High

777990

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

777992

HIF1A
Hypoxia-inducible factor 1-alpha

1

4

High-throughput

0.479

High

777993

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

777994

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.479

High

778006

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

778007

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

778008

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

778011

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

778015

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

778016

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.479

High

778018

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

778020

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

778024

CIC
Protein capicua homolog

1

9

High-throughput

0.479

High

778025

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.479

High

778027

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

5

High-throughput

0.479

High

778029

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

3

Small-scale

0.479

High

778030

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.479

High

778032

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

778033

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

778034

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

778035

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

778036

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

5

High-throughput

0.479

High

778038

ECT2
Protein ECT2

1

3

High-throughput

0.479

High

778039

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

778041

ANLN
Anillin

1

3

High-throughput

0.479

High

778042

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

778050

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

778053

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

778054

FAF1
FAS-associated factor 1

1

2

High-throughput

0.479

High

778056

FAN1
Fanconi-associated nuclease 1

1

1

Small-scale

0.479

High

778059

MAFB
Transcription factor MafB

1

7

High-throughput

0.479

High

778055

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

3

High-throughput

0.470

High

161792

ZN263
Zinc finger protein 263

1

0

Small-scale

0.458

High

182590

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

262382

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

503590

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

532412

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

582112

NUCL
Nucleolin

1

0

High-throughput

0.458

High

719398

MERL
Merlin

1

0

High-throughput

0.458

High

734548

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.458

High

777960

TXTP
Tricarboxylate transport protein, mitochondrial

1

0

High-throughput

0.458

High

777964

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

777969

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

777974

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

777995

DDR2
Discoidin domain-containing receptor 2

1

3

High-throughput

0.457

High

401565

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

496483

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

778013

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

129711

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

1

High-throughput

0.437

High

148485

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

384419

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

777983

TRI29
Tripartite motif-containing protein 29

1

4

Small-scale

0.437

High

777999

RC3H1
Roquin-1

1

2

High-throughput

0.437

High

778001

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

778005

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

778022

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

778037

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

778040

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.437

High

778058

PHLA3
Pleckstrin homology-like domain family A member 3

1

1

High-throughput

0.437

High

777957

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

961

SIM26
Small integral membrane protein 26

1

2

High-throughput

0.407

High

777991

FSCN1
Fascin

1

1

Small-scale

0.407

High

777997

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.407

High

778004

PKHG7
Pleckstrin homology domain-containing family G member 7

1

5

High-throughput

0.407

High

545079

PVR
Poliovirus receptor

2

0

High-throughput

0.328

High

778002

ANR40
Ankyrin repeat domain-containing protein 40

2

0

High-throughput

0.316

High

146323

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.279

Low

224906

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

702332

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

777998

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

778012

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

778047

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

777984

MESD
LRP chaperone MESD

1

0

High-throughput

0.265

Low

541220

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

777963

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.249

Low

777996

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

778003

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

778009

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

778017

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

778045

MTMR4
Myotubularin-related protein 4

1

0

High-throughput

0.249

Low

778052

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024