HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: TRIB3 (Q96RU7)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B)
Gene: TRIB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 548 Hs			1 358
+	Hs
		1301548 TCPH_HUMAN (9-538): 0: 564: 26.39		TRIB3_HUMAN (1-358): 9.23e-169: 476: 100.00
+	Hs
		826833 TCPG_HUMAN (10-547): 0: 558: 28.21		TRIB3_HUMAN (1-358): 9.23e-169: 476: 100.00
+	Hs
		681746 TCPQ_HUMAN (1-548): 0: 616: 100.00		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Hs
		821371 TCPE_HUMAN (2-524): 0: 535: 29.62		TRIB3_HUMAN (1-358): 9.23e-169: 476: 100.00
+	Hs
		843343 TCPD_HUMAN (19-525): 0: 530: 28.24		TRIB3_HUMAN (1-358): 9.23e-169: 476: 100.00
+	Hs
		573430 TCPA_HUMAN (21-541): 0: 528: 29.89		TRIB3_HUMAN (1-358): 9.23e-169: 476: 100.00
+	Hs
		568592 TCPQ_HUMAN (1-548): 0: 616: 100.00		KAPCA_HUMAN (56-352): 4.79e-131: 380: 20.26
+	Hs
		681999 TCPH_HUMAN (9-538): 0: 564: 26.39		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Hs
		681738 TCPG_HUMAN (10-547): 0: 558: 28.21		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Dm
		1179613 Q7K3J0_DROME (1-544): 0: 553: 61.65		AKT1_DROME (45-356): 7.26e-135: 399: 16.87
+	Hs
		681735 TCPE_HUMAN (2-524): 0: 535: 29.62		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Hs
		681747 TCPD_HUMAN (19-525): 0: 530: 28.24		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Hs
		573141 TCPA_HUMAN (21-541): 0: 528: 29.89		AKT1_HUMAN (3-352): 2.61e-138: 403: 17.62
+	Dm
		1213398 Q9VHL2_DROME (12-532): 0: 527: 26.65		AKT1_DROME (45-356): 7.26e-135: 399: 16.87
+	Hs
		568585 TCPE_HUMAN (2-524): 0: 535: 29.62		KAPCA_HUMAN (56-352): 4.79e-131: 380: 20.26
+	Hs
		568593 TCPD_HUMAN (19-525): 0: 530: 28.24		KAPCA_HUMAN (56-352): 4.79e-131: 380: 20.26
+	Hs
		821309 TCPE_HUMAN (2-524): 0: 535: 29.62		STK40_HUMAN (145-310): 4.15e-25: 107: 38.10
+	Hs
		1039155 TCPQM_HUMAN (32-545): 7.5e-75: 249: 32.17		KCC2D_HUMAN (61-317): 2.58e-23: 102: 28.47