Protein: NAGK
N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) (Muramyl dipeptide kinase) (EC 2.7.1.-) (N-acetyl-D-mannosamine kinase) (EC 2.7.1.60)

Gene: NAGK
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q9UJ70

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006044 - N-acetylglucosamine metabolic process
GO:0006046 - N-acetylglucosamine catabolic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1460547

NAGK
N-acetyl-D-glucosamine kinase

3

0

High-throughput

0.835

High

1460222

DACH1
Dachshund homolog 1

5

0

High-throughput

0.694

High

843001

CDN2C
Cyclin-dependent kinase 4 inhibitor C

3

1

High-throughput

0.683

High

140477

SDCB1
Syntenin-1

3

2

High-throughput

0.675

High

1392950

NTAQ1
Protein N-terminal glutamine amidohydrolase

3

0

High-throughput

0.643

High

1348565

LNX1
E3 ubiquitin-protein ligase LNX

4

2

High-throughput

0.640

High

569345

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

4

1

High-throughput

0.629

High

729490

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

1

High-throughput

0.628

High

540101

BCR
Breakpoint cluster region protein

2

0

High-throughput

0.602

High

756080

MCM5
DNA replication licensing factor MCM5

2

0

High-throughput

0.602

High

1287146

PATL1
Protein PAT1 homolog 1

2

0

High-throughput

0.602

High

1295454

C2CD5
C2 domain-containing protein 5

2

0

High-throughput

0.602

High

1316477

XRN1
5'-3' exoribonuclease 1

2

0

High-throughput

0.602

High

1338781

ARI1B
AT-rich interactive domain-containing protein 1B

2

0

High-throughput

0.602

High

1439299

E41L5
Band 4.1-like protein 5

2

0

High-throughput

0.602

High

1460556

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

2

0

High-throughput

0.585

High

1146288

ANKR1
Ankyrin repeat domain-containing protein 1

2

0

High-throughput

0.580

High

604876

HXB9
Homeobox protein Hox-B9

2

3

High-throughput

0.574

High

605029

HXB6
Homeobox protein Hox-B6

2

2

High-throughput

0.574

High

1150843

SF01
Splicing factor 1

2

1

High-throughput

0.574

High

1219155

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

1

High-throughput

0.574

High

1279180

RAI1
Retinoic acid-induced protein 1

2

1

High-throughput

0.574

High

1404157

CNN2
Calponin-2

2

1

High-throughput

0.574

High

1049050

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.573

High

291876

STK16
Serine/threonine-protein kinase 16

1

0

Small-scale

0.549

High

1452951

ARP10
Actin-related protein 10

1

0

High-throughput

0.549

High

670033

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.536

High

938828

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

1

High-throughput

0.536

High

1460555

RN115
E3 ubiquitin-protein ligase RNF115

1

2

High-throughput

0.536

High

1460551

NUDC
Nuclear migration protein nudC

1

0

Small-scale

0.529

High

893752

MEOX1
Homeobox protein MOX-1

1

3

High-throughput

0.523

High

1389133

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.518

High

132676

UPK1A
Uroplakin-1a

1

0

High-throughput

0.513

High

194482

P2RX6
P2X purinoceptor 6

1

0

High-throughput

0.513

High

229100

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.513

High

602848

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

908646

PRELP
Prolargin

1

0

High-throughput

0.513

High

943156

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

976644

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

1091169

FOXC1
Forkhead box protein C1

1

0

High-throughput

0.513

High

1179257

ERC6L
DNA excision repair protein ERCC-6-like

1

0

High-throughput

0.513

High

1197121

AMOT
Angiomotin

1

0

High-throughput

0.513

High

1356416

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.513

High

1417091

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

1448005

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1460554

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.513

High

1325774

LNX2
Ligand of Numb protein X 2

1

2

High-throughput

0.512

High

181955

SMAD9
Mothers against decapentaplegic homolog 9

1

1

High-throughput

0.508

High

1153940

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.508

High

562475

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

937131

CASP6
Caspase-6

1

0

High-throughput

0.493

High

1460553

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

724986

HXA7
Homeobox protein Hox-A7

1

2

High-throughput

0.489

High

1229155

FRPD2
FERM and PDZ domain-containing protein 2

1

1

High-throughput

0.489

High

1453956

RN181
E3 ubiquitin-protein ligase RNF181

1

2

High-throughput

0.489

High

1460453

PHF11
PHD finger protein 11

1

1

High-throughput

0.489

High

156676

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

0

High-throughput

0.486

High

342056

CEP43
Centrosomal protein 43

1

0

High-throughput

0.486

High

568597

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.486

High

573274

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.486

High

1279792

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.486

High

1306931

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.486

High

1338187

PPHLN
Periphilin-1

1

0

High-throughput

0.486

High

1006782

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.480

High

159908

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

73634

B2R7W0
cDNA, FLJ93628, Homo sapiens methylene tetrahydrofolate dehydrogenase

1

1

High-throughput

0.470

High

1250055

WDR82
WD repeat-containing protein 82

1

1

High-throughput

0.464

High

243233

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

292875

GRAP2
GRB2-related adapter protein 2

1

0

High-throughput

0.458

High

316127

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

386348

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

831610

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

872858

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1333365

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

1335052

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1336008

SMIP6
Sperm microtubule inner protein 6

1

0

High-throughput

0.458

High

1339220

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1380684

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1460548

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.458

High

1339859

PJA1
E3 ubiquitin-protein ligase Praja-1

1

2

Small-scale

0.457

High

626394

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.445

High

1448544

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1224930

TENS2
Tensin-2

1

1

High-throughput

0.437

High

1460550

LIMC1
LIM and calponin homology domains-containing protein 1

1

1

High-throughput

0.437

High

142437

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

404943

PRIO
Major prion protein

1

0

High-throughput

0.426

High

564524

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

935259

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1227664

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1235010

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1447610

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

330364

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.407

High

682117

RBTN1
Rhombotin-1

3

0

High-throughput

0.350

High

212862

ZBT43
Zinc finger and BTB domain-containing protein 43

2

0

High-throughput

0.328

High

336241

ZIC2
Zinc finger protein ZIC 2

2

0

High-throughput

0.328

High

553772

MYCL
Protein L-Myc

2

0

High-throughput

0.328

High

790183

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

2

0

High-throughput

0.328

High

888684

YLPM1
YLP motif-containing protein 1

2

0

High-throughput

0.328

High

928581

TERF1
Telomeric repeat-binding factor 1

2

0

High-throughput

0.328

High

1005514

RBM6
RNA-binding protein 6

2

0

High-throughput

0.328

High

1023299

RBM3
RNA-binding protein 3

2

0

High-throughput

0.328

High

1103075

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

2

0

High-throughput

0.328

High

1206569

PRC2B
Protein PRRC2B

2

0

High-throughput

0.328

High

1420659

SETD5
Histone-lysine N-methyltransferase SETD5

2

0

High-throughput

0.328

High

1460549

SCAF8
SR-related and CTD-associated factor 8

2

0

High-throughput

0.328

High

1403953

HTF4
Transcription factor 12

1

0

High-throughput

0.299

High

1208155

CD158
Coiled-coil domain-containing protein 158

1

0

High-throughput

0.282

High

325365

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

505112

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

552437

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.279

Low

608379

EGLN
Endoglin

1

0

High-throughput

0.279

Low

733462

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

1181353

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

1216492

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.279

Low

1254167

SHSA6
Protein shisa-6

1

0

High-throughput

0.279

Low

1292355

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1306992

CERS3
Ceramide synthase 3

1

0

High-throughput

0.279

Low

1316009

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1358795

ZDH19
Palmitoyltransferase ZDHHC19

1

0

High-throughput

0.279

Low

1372230

TATD2
3'-5' RNA nuclease TATDN2

1

0

High-throughput

0.279

Low

1380562

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

1385217

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1393013

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.279

Low

1408252

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1413545

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.279

Low

1414007

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1450677

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low

1454268

STIM2
Stromal interaction molecule 2

1

0

High-throughput

0.279

Low

1460552

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

441572

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

1148077

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.265

Low

1323901

SYNE4
Nesprin-4

1

0

High-throughput

0.265

Low

1385272

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.265

Low

1199902

LACB2
Endoribonuclease LACTB2

1

0

High-throughput

0.251

Low

106817

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

176096

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.249

Low

353615

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

769458

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1179270

CB068
UPF0561 protein C2orf68

1

0

High-throughput

0.249

Low

1256008

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1404994

GA2L1
GAS2-like protein 1

1

0

High-throughput

0.249

Low

1446090

DLRB1
Dynein light chain roadblock-type 1

1

0

Small-scale

0.249

Low

947076

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

261310

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

1104159

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1145558

RBBP5
Retinoblastoma-binding protein 5

1

0

High-throughput

0.232

Low

1454835

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025