HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.596

Property	Details
Experiments	32814053, 17500595
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043065 - positive regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 480
+	Hs
		727714 HD_HUMAN (1-3142): 0: 5724: 100.00		DNJA1_HUMAN (89-468): 4.77e-124: 369: 26.43
+	Hs
		258794 HD_HUMAN (1-3142): 0: 5724: 100.00		DNJA2_HUMAN (89-465): 5.1e-123: 366: 26.38
+	Mm
		108600 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		DNJA1_MOUSE (89-468): 4.13e-123: 366: 26.19
+	Mm
		108928 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		DNJA2_MOUSE (89-465): 5.61e-122: 364: 26.38