HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSB6 (P28072)
Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y)
Gene: PSMB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 239
+	Dm
		771294 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q7K148_DROME (31-218): 1.61e-87: 262: 30.69
+	Dm
		47598 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		A0AQH0_DROME (25-237): 3.01e-87: 259: 57.28
+	Hs
		637732 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB7_HUMAN (28-229): 2.05e-84: 254: 30.69
+	Hs
		637631 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (3-230): 3.68e-84: 252: 18.75
+	Dm
		771324 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q9VUJ1_DROME (37-219): 6.67e-85: 255: 28.96
+	Hs
		637626 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA4_HUMAN (6-232): 2.37e-82: 248: 15.19
+	Ss
		94704 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F2Z5K2_PIG (3-230): 3.68e-84: 252: 18.75
+	Dm
		771302 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q8T8V8_DROME (28-218): 9.31e-83: 251: 29.69
+	Hs
		637630 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB9_HUMAN (30-231): 1.12e-81: 245: 62.38
+	Dm
		771303 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSA5_DROME (3-232): 7.65e-83: 248: 17.62
+	Hs
		156224 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA7_HUMAN (8-231): 4.14e-80: 242: 18.03
+	Hs
		637640 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB10_HUMAN (28-236): 9.34e-80: 242: 27.62
+	Ss
		94582 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F1SBA5_PIG (6-229): 8.25e-82: 246: 18.03
+	Hs
		637633 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB6_HUMAN (1-239): 1.24e-79: 240: 100.00
+	Ss
		94705 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		G3DRF8_PIG (1-238): 1.38e-80: 243: 96.22
+	Hs
		637629 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB8_HUMAN (12-218): 2.72e-77: 236: 31.28
+	Hs
		637634 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB5_HUMAN (13-235): 4.14e-75: 230: 30.36
+	Ce
		1278563 PSA4_CAEEL (1-178): 8.98e-71: 216: 64.61		PSA7_CAEEL (9-232): 6.48e-81: 244: 17.45
+	Hs
		156226 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA7_HUMAN (8-231): 4.14e-80: 242: 18.03
+	Dm
		184454 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		O17311_DROME (31-220): 1.14e-73: 226: 29.47