HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: PHLB1 (Q86UU1)
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)
Gene: PHLDB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	29395067, 21653829
Identification Methods	proximity labelling technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 1377
+	Hs
		843774 FXR1_HUMAN (14-673): 0: 798: 51.34		PHLB1_HUMAN (1-1377): 0: 593: 100.00
+	Hs
		844029 FXR2_HUMAN (1-673): 0: 1004: 100.00		KIF1A_HUMAN (14-211): 7.08e-43: 173: 20.64
+	Hs
		844072 FXR2_HUMAN (1-673): 0: 1004: 100.00		KIF14_HUMAN (14-232): 2.54e-35: 149: 23.66
+	Mm
		1142910 FXR1_MOUSE (14-673): 0: 981: 62.83		AFAD_MOUSE (27-275): 1.32e-36: 153: 20.29
+	Hs
		148550 FXR2_HUMAN (1-673): 0: 1004: 100.00		CTRO_HUMAN (478-1126): 1.29e-19: 98.1: 12.89
+	Hs
		725117 FXR2_HUMAN (1-673): 0: 1004: 100.00		MYH10_HUMAN (138-864): 2.8e-15: 83.9: 7.68
+	Mm
		1142920 FXR1_MOUSE (14-673): 0: 981: 62.83		ITSN1_MOUSE (209-861): 1.66e-15: 84.6: 11.60
+	Mm
		1142850 FXR1_MOUSE (14-673): 0: 981: 62.83		AKAP9_MOUSE (560-1207): 2.92e-10: 67.4: 12.46
+	Hs
		843684 FXR1_HUMAN (14-673): 0: 798: 51.34		KIF14_HUMAN (14-232): 2.54e-35: 149: 23.66
+	Hs
		148549 FXR1_HUMAN (14-673): 0: 798: 51.34		CTRO_HUMAN (478-1126): 1.29e-19: 98.1: 12.89
+	Hs
		725116 FXR1_HUMAN (14-673): 0: 798: 51.34		MYH10_HUMAN (138-864): 2.8e-15: 83.9: 7.68
+	Hs
		724719 FXR1_HUMAN (14-673): 0: 798: 51.34		MYH9_HUMAN (133-878): 3.34e-14: 80.4: 9.49
+	Mm
		1207077 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		GOGA4_MOUSE (134-1245): 1.63e-27: 123: 8.73
+	Mm
		1174194 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		AKAP9_MOUSE (560-1207): 2.92e-10: 67.4: 12.46
+	Hs
		231504 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		KIF1B_HUMAN (14-207): 6.12e-42: 171: 22.43
+	Hs
		988893 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		KIF14_HUMAN (14-232): 2.54e-35: 149: 23.66
+	Mm
		729574 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		GOGA4_MOUSE (134-1245): 1.63e-27: 123: 8.73
+	Mm
		729526 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		AKAP9_MOUSE (560-1207): 2.92e-10: 67.4: 12.46