HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0010494 - cytoplasmic stress granule GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 673 Hs			1 1191
+	Hs
		843915 FXR1_HUMAN (14-673): 0: 798: 51.34		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		844105 FXR2_HUMAN (1-673): 0: 1004: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		843728 FXR1_HUMAN (14-673): 0: 798: 51.34		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		844130 FXR2_HUMAN (1-673): 0: 1004: 100.00		PHLB1_HUMAN (460-1100): 1.63e-72: 267: 14.85
+	Hs
		257588 FXR2_HUMAN (1-673): 0: 1004: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		325663 FXR2_HUMAN (1-673): 0: 1004: 100.00		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		844222 FXR2_HUMAN (1-673): 0: 1004: 100.00		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82
+	Hs
		843774 FXR1_HUMAN (14-673): 0: 798: 51.34		PHLB1_HUMAN (460-1100): 1.63e-72: 267: 14.85
+	Mm
		102653 FXR1_MOUSE (14-673): 0: 981: 62.83		G3X972_MOUSE (500-826): 7.28e-14: 78.8: 11.78
+	Hs
		988938 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		257587 FXR1_HUMAN (14-673): 0: 798: 51.34		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		843883 FXR1_HUMAN (14-673): 0: 798: 51.34		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82
+	Mm
		57191 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		CHD7_MOUSE (412-954): 1.27e-16: 88.2: 7.87
+	Mm
		1157641 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		IF4G1_MOUSE (575-1137): 6.45e-15: 82.4: 11.00
+	Mm
		1207085 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		ANR17_MOUSE (342-843): 4.94e-09: 63.1: 8.87
+	Mm
		57183 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		CHD7_MOUSE (412-954): 1.27e-16: 88.2: 7.87
+	Mm
		729510 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		IF4G1_MOUSE (575-1137): 6.45e-15: 82.4: 11.00
+	Hs
		257605 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Mm
		729583 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		ANR17_MOUSE (342-843): 4.94e-09: 63.1: 8.87
+	Hs
		989097 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82