HitPredict

Interactor 1: GRAM (P51124)
Granzyme M (EC 3.4.21.-) (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease)
Gene: GZMM

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.50	0.520

Property	Details
Experiments	18523284
Identification Methods	enzymatic study, protease assay
Interaction Type	direct interaction, protein cleavage

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Hs			1 451
+	Hs
		844336 GRAM_HUMAN (1-257): 1.22e-107: 313: 100.00		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1309494 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		714751 TRY3_HUMAN (12-257): 1.2e-104: 307: 32.80		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		1309527 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		933614 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1175177 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		933221 PRSS8_HUMAN (14-253): 7.09e-98: 291: 29.41		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		933653 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		933554 KLK6_HUMAN (5-255): 1.94e-97: 286: 31.50		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1175223 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428427 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933971 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Mm
		371482 CFAD_MOUSE (1-253): 1.38e-49: 165: 35.66		TBA1B_MOUSE (1-440): 0: 717: 100.00
+	Mm
		371765 CFAD_MOUSE (1-253): 1.38e-49: 165: 35.66		TBB4B_MOUSE (1-437): 0: 697: 40.96
+	Hs
		595562 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		595527 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		486167 GRAB_HUMAN (25-255): 4.24e-39: 137: 36.82		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		595544 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428017 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428023 PRTN3_HUMAN (25-255): 1.19e-33: 124: 37.24		TBB5_HUMAN (1-439): 0: 699: 41.23