HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	34079125, 16944923
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0008284 - positive regulation of cell population proliferation and 5 others more... GO:0032991 - protein-containing complex GO:0035633 - maintenance of blood-brain barrier GO:0043296 - apical junction complex GO:0070160 - tight junction GO:0071896 - protein localization to adherens junction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	375
Hs

1	1748

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024