HitPredict

Interactor 1: DVL1 (P51141)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: VANG1 (Q80Z96)
Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1)
Gene: Vangl1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	15456783
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016328 - lateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 695 Mm			1 526
+	Mm
		1142090 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		VANG1_MOUSE (1-526): 0: 816: 100.00
+	Hs
		1250791 DVL3_HUMAN (1-695): 6.34e-165: 492: 61.11		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Mm
		1141500 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		VANG1_MOUSE (1-526): 0: 816: 100.00
+	Mm
		844432 DVL1_MOUSE (1-695): 0: 602: 100.00		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Hs
		151096 DVL2_HUMAN (3-695): 2.79e-147: 448: 57.75		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Mm
		1142094 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Hs
		1273675 DVL3_HUMAN (1-695): 6.34e-165: 492: 61.11		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Mm
		1141507 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Hs
		151251 DVL2_HUMAN (3-695): 2.79e-147: 448: 57.75		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Dm
		219854 DSH_DROME (2-541): 3.77e-110: 348: 46.58		O45030_DROME (21-526): 0: 679: 44.85
+	Dm
		52640 DSH_DROME (2-541): 3.77e-110: 348: 46.58		A1Z7N9_DROME (21-526): 0: 679: 44.85
+	Hs
		1250786 PARD3_HUMAN (27-541): 1.26e-45: 177: 16.45		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Ce
		109389 Q18239_CAEEL (4-513): 7.34e-91: 301: 32.97		H2KY90_CAEEL (49-526): 0: 664: 34.72
+	Hs
		883931 SYJ2B_HUMAN (249-324): 9.99e-16: 76.5: 35.00		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Hs
		1200024 RIMS1_HUMAN (8-655): 1.32e-45: 178: 14.63		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Hs
		1256921 PARD3_HUMAN (27-541): 1.26e-45: 177: 16.45		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Ce
		101922 G1K0W3_CAEEL (239-433): 4.76e-39: 156: 25.48		H2KY90_CAEEL (49-526): 0: 664: 34.72
+	Dm
		219853 DLG1_DROME (204-338): 5.07e-15: 81.1: 27.97		O45030_DROME (21-526): 0: 679: 44.85
+	Dm
		52639 DLG1_DROME (204-338): 5.07e-15: 81.1: 27.97		A1Z7N9_DROME (21-526): 0: 679: 44.85
+	Hs
		883951 SYJ2B_HUMAN (249-324): 9.99e-16: 76.5: 35.00		VANG2_HUMAN (1-526): 0: 658: 71.21