HitPredict

Interactor 1: DVL1 (P51141)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: NKD2 (Q8VE28)
Protein naked cuticle homolog 2 (Naked-2) (mNkd2)
Gene: NKD2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	11356022
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016055 - Wnt signaling pathway GO:0016328 - lateral plasma membrane GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 695 Mm			1 461
+	Mm
		844433 DVL1_MOUSE (1-695): 0: 602: 100.00		NKD1_MOUSE (1-440): 0: 548: 42.37
+	Hs
		150741 DVL1_HUMAN (1-695): 0: 569: 94.83		NKD1_HUMAN (1-440): 0: 554: 41.25
+	Hs
		150740 DVL1_HUMAN (1-695): 0: 569: 94.83		NKD2_HUMAN (1-440): 0: 543: 74.89
+	Mm
		1142093 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		NKD2_MOUSE (1-461): 0: 598: 100.00
+	Mm
		1141506 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		NKD2_MOUSE (1-461): 0: 598: 100.00
+	Hs
		1273595 DVL3_HUMAN (1-695): 6.34e-165: 492: 61.11		NKD1_HUMAN (1-440): 0: 554: 41.25
+	Mm
		1142095 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		NKD1_MOUSE (1-440): 0: 548: 42.37
+	Mm
		1141508 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		NKD1_MOUSE (1-440): 0: 548: 42.37
+	Dr
		60241 F1QNA4_DANRE (1-695): 6.5e-168: 500: 64.24		NKD2_DANRE (1-418): 3.04e-146: 425: 41.63
+	Dm
		844395 DSH_DROME (2-541): 3.77e-110: 348: 46.58		NKD_DROME (113-192): 2.25e-22: 102: 39.29