HitPredict

Interactor 1: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Interactor 2: PKHM2 (Q8IWE5)
Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2) (Salmonella-induced filaments A and kinesin-interacting protein) (SifA and kinesin-interacting protein)
Gene: PLEKHM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.785

Property	Details
Experiments	34079125, 18787122
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PH~Ras, RUN~Ras
Common GO terms	GO:0032880 - regulation of protein localization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 1019
+	Hs
		845059 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		PKHM2_HUMAN (1-1019): 0: 1490: 100.00
+	Hs
		845381 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		PKHM1_HUMAN (1-446): 2.39e-84: 296: 22.24
+	Hs
		845020 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		RUFY3_HUMAN (6-403): 3.59e-86: 287: 17.17
+	Hs
		845561 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		RUFY3_HUMAN (6-403): 3.59e-86: 287: 17.17
+	Hs
		845205 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		FYCO1_HUMAN (8-429): 4.71e-74: 270: 14.84
+	Hs
		845112 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		RUFY2_HUMAN (2-431): 1.68e-77: 267: 15.79
+	Hs
		845697 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		FYCO1_HUMAN (8-429): 4.71e-74: 270: 14.84
+	Hs
		845637 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		RUFY2_HUMAN (2-431): 1.68e-77: 267: 15.79
+	Hs
		845178 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		RUN3B_HUMAN (6-406): 1.27e-72: 250: 14.92
+	Hs
		1070359 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		RUFY1_HUMAN (5-421): 4.79e-69: 246: 16.27
+	Hs
		1070318 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		SNX29_HUMAN (5-418): 4.64e-66: 240: 20.82
+	Hs
		845102 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		SNX29_HUMAN (5-418): 4.64e-66: 240: 20.82
+	Hs
		845689 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		RUFY1_HUMAN (5-421): 4.79e-69: 246: 16.27
+	Hs
		845629 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		SNX29_HUMAN (5-418): 4.64e-66: 240: 20.82
+	Hs
		1070261 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		DEN5B_HUMAN (8-397): 2.6e-59: 224: 12.85
+	Hs
		845645 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		RUBIC_HUMAN (3-428): 5.37e-62: 230: 15.74
+	Hs
		914301 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		RUFY1_HUMAN (5-421): 4.79e-69: 246: 16.27
+	Dm
		284095 RAB7_DROME (1-180): 6.29e-65: 200: 51.93		Q9W293_DROME (6-414): 6.19e-77: 269: 17.69
+	Hs
		914156 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		DEN5B_HUMAN (8-397): 2.6e-59: 224: 12.85