HitPredict

Interactor 1: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~HSA, Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1590 Hs			1 376
+	Hs
		846742 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Mm
		929795 SMCA2_MOUSE (1-1590): 0: 1055: 94.38		ACTG_MOUSE (3-376): 0: 595: 91.44
+	Mm
		929785 SMCA4_MOUSE (40-1588): 0: 986: 72.81		ACTG_MOUSE (3-376): 0: 595: 91.44
+	Hs
		846910 SMCA4_HUMAN (40-1588): 0: 977: 72.70		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		846917 SMCA4_HUMAN (40-1588): 0: 977: 72.70		ACTG_HUMAN (3-376): 0: 595: 91.44
+	Hs
		846918 SMCA4_HUMAN (40-1588): 0: 977: 72.70		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Hs
		846919 SMCA4_HUMAN (40-1588): 0: 977: 72.70		ACTS_HUMAN (2-376): 0: 590: 87.47
+	Xl
		292752 Q4VQ79_XENLA (66-1590): 0: 961: 72.95		ACTB_XENLA (3-376): 0: 596: 91.18
+	Dm
		501486 BRM_DROME (21-1578): 0: 881: 50.85		ACT1_DROME (1-376): 0: 599: 90.69
+	Dm
		361138 BRM_DROME (21-1578): 0: 881: 50.85		ACT2_DROME (1-376): 0: 596: 90.16
+	Hs
		229358 SMCA5_HUMAN (610-1584): 0: 803: 27.43		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Zm
		13638 A0A1D6MT91_MAIZE (576-1585): 0: 798: 27.52		A0A1D6FW13_MAIZE (2-376): 0: 585: 83.47
+	Hs
		891769 CHD4_HUMAN (370-1589): 0: 749: 22.31		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		932158 CHD4_HUMAN (370-1589): 0: 749: 22.31		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Hs
		891731 CHD3_HUMAN (415-1590): 0: 725: 23.92		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		929837 CHD3_HUMAN (415-1590): 0: 725: 23.92		ACTG_HUMAN (3-376): 0: 595: 91.44
+	Hs
		932125 CHD3_HUMAN (415-1590): 0: 725: 23.92		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Mm
		929800 EP400_MOUSE (1048-1192): 6.84e-45: 181: 39.31		ACTG_MOUSE (3-376): 0: 595: 91.44