HitPredict

Interactor 1: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Interactor 2: BAZ1A (Q9NRL2)
Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1)
Gene: BAZ1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16877760
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain, Bromodomain~PHD
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1590 Hs			1 1556
+	Hs
		600103 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		TAF1_HUMAN (668-1543): 1.33e-83: 306: 11.86
+	Hs
		846760 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		EP300_HUMAN (794-1537): 2.78e-72: 270: 11.46
+	Hs
		846837 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		CBP_HUMAN (1239-1530): 5.46e-40: 165: 15.50
+	Hs
		846947 SMCA4_HUMAN (40-1588): 0: 977: 72.70		EP300_HUMAN (794-1537): 2.78e-72: 270: 11.46
+	Hs
		846838 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		KAT2B_HUMAN (1417-1535): 1.83e-38: 158: 26.05
+	Hs
		631379 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		BRD2_HUMAN (1369-1538): 1.74e-30: 132: 19.19
+	Hs
		846778 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		BRD3_HUMAN (1419-1533): 1.46e-27: 122: 27.97
+	Hs
		846812 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		PB1_HUMAN (1264-1556): 1.76e-22: 107: 15.53
+	Mm
		1150298 SMCA2_MOUSE (1-1590): 0: 1055: 94.38		BAZ1B_MOUSE (1210-1535): 1.97e-27: 123: 14.37
+	Hs
		847033 SMCA4_HUMAN (40-1588): 0: 977: 72.70		PHIP_HUMAN (1179-1555): 1.3e-40: 167: 14.29
+	Hs
		847041 SMCA4_HUMAN (40-1588): 0: 977: 72.70		CBP_HUMAN (1239-1530): 5.46e-40: 165: 15.50
+	Mm
		101535 SMCA2_MOUSE (1-1590): 0: 1055: 94.38		F8VQD1_MOUSE (1391-1536): 5.22e-16: 86.5: 19.74
+	Hs
		631380 SMCA4_HUMAN (40-1588): 0: 977: 72.70		BRD2_HUMAN (1369-1538): 1.74e-30: 132: 19.19
+	Hs
		846977 SMCA4_HUMAN (40-1588): 0: 977: 72.70		BRD3_HUMAN (1419-1533): 1.46e-27: 122: 27.97
+	Hs
		846993 SMCA4_HUMAN (40-1588): 0: 977: 72.70		BRDT_HUMAN (1381-1533): 1.08e-24: 114: 23.53
+	Hs
		847007 SMCA4_HUMAN (40-1588): 0: 977: 72.70		PB1_HUMAN (1264-1556): 1.76e-22: 107: 15.53
+	Mm
		1111945 SMCA4_MOUSE (40-1588): 0: 986: 72.81		PB1_MOUSE (1391-1536): 4.14e-16: 86.9: 19.74
+	Mm
		101533 SMCA4_MOUSE (40-1588): 0: 986: 72.81		F8VQD1_MOUSE (1391-1536): 5.22e-16: 86.5: 19.74
+	Hs
		847042 SMCA4_HUMAN (40-1588): 0: 977: 72.70		KAT6A_HUMAN (1151-1208): 7.5e-09: 63.2: 44.07
+	Sp
		1336887 SNF21_SCHPO (418-1509): 0: 830: 40.75		YK82_SCHPO (1228-1532): 5.72e-32: 136: 14.70