HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: STAT2 (P52630)
Signal transducer and activator of transcription 2 (p113)
Gene: STAT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	12244326
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1647 Hs			1 851
+	Hs
		786278 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		STAT1_HUMAN (1-728): 0: 879: 42.36
+	Hs
		776612 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		STAT3_HUMAN (1-747): 0: 846: 37.47
+	Hs
		786592 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		STA5A_HUMAN (1-769): 0: 789: 24.67
+	Hs
		786277 SMCA2_HUMAN (1-1647): 0: 980: 71.69		STAT1_HUMAN (1-728): 0: 879: 42.36
+	Mm
		786527 CHD8_MOUSE (18-1527): 0: 718: 20.36		STAT3_MOUSE (1-747): 0: 846: 37.47