Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2
Interactor 2: SEM1 (P60896)
26S proteasome complex subunit SEM1 (26S proteasome complex subunit DSS1) (Deleted in split hand/split foot protein 1) (Split hand/foot deleted protein 1) (Split hand/foot malformation type 1 protein)
Gene: SEM1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.929 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26145171, 26833090, 10373512, 32609828, 12228710, 33978741, 16205630, 28976962, 16239144, 24013206, 22293751 |
| Identification Methods | biochemical, pull down, affinity chromatography technology, two hybrid, x-ray crystallography, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BRCA-2_helical~DSS1_SEM1, BRCA-2_OB1~DSS1_SEM1 |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
