Protein: PEX1
Peroxisomal ATPase PEX1 (EC 3.6.4.-) (Peroxin-1) (Peroxisome biogenesis disorder protein 1) (Peroxisome biogenesis factor 1)

Gene: PEX1
Organism: Homo sapiens
Interactions: 131
UniProt ID: O43933

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

231699

PEX6
Peroxisomal ATPase PEX6

2

17

Small-scale

0.821

High

231693

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

9

High-throughput

0.691

High

231748

EFMT3
EEF1A lysine methyltransferase 3

1

6

High-throughput

0.691

High

231679

TNR6
Tumor necrosis factor receptor superfamily member 6

3

4

High-throughput

0.667

High

231670

ICAM1
Intercellular adhesion molecule 1

2

2

High-throughput

0.628

High

231720

PEX26
Peroxisome assembly protein 26

2

1

Small-scale

0.619

High

231689

TERA
Transitional endoplasmic reticulum ATPase

1

17

Small-scale

0.618

High

231777

UBQL2
Ubiquilin-2

1

9

High-throughput

0.618

High

231686

PEX5
Peroxisomal targeting signal 1 receptor

2

5

Small-scale

0.595

High

231738

F174A
Membrane protein FAM174A

2

3

High-throughput

0.574

High

231780

DKKL1
Dickkopf-like protein 1

2

3

High-throughput

0.574

High

231662

PEX14
Peroxisomal membrane protein PEX14

2

2

Small-scale

0.571

High

174465

TRI66
Tripartite motif-containing protein 66

1

9

High-throughput

0.553

High

231666

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.553

High

231664

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.536

High

231668

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

231669

DYR
Dihydrofolate reductase

1

1

High-throughput

0.536

High

231701

EXOS2
Exosome complex component RRP4

1

2

High-throughput

0.536

High

231702

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

6

High-throughput

0.536

High

231703

SMC1A
Structural maintenance of chromosomes protein 1A

1

1

High-throughput

0.536

High

231710

EFMT2
EEF1A lysine methyltransferase 2

1

1

High-throughput

0.536

High

231722

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

1

High-throughput

0.536

High

231733

ARRD4
Arrestin domain-containing protein 4

1

2

High-throughput

0.536

High

231736

ARRD2
Arrestin domain-containing protein 2

1

2

High-throughput

0.536

High

231751

TCPQM
T-complex protein 1 subunit theta-like 2

1

12

High-throughput

0.536

High

231756

NAA11
N-alpha-acetyltransferase 11

1

2

High-throughput

0.536

High

231757

DUS16
Dual specificity protein phosphatase 16

1

4

High-throughput

0.536

High

231758

UBXN6
UBX domain-containing protein 6

1

8

High-throughput

0.536

High

231761

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.536

High

231763

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

3

High-throughput

0.536

High

231785

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

2

High-throughput

0.536

High

131604

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.515

High

210444

MSH5
MutS protein homolog 5

1

2

High-throughput

0.515

High

231661

IF2P
Eukaryotic translation initiation factor 5B

1

4

High-throughput

0.515

High

231672

ANXA8
Annexin A8

1

7

High-throughput

0.515

High

231682

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.515

High

231684

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

3

High-throughput

0.515

High

231695

H31
Histone H3.1

1

6

High-throughput

0.515

High

231706

BATF
Basic leucine zipper transcriptional factor ATF-like

1

2

High-throughput

0.515

High

231712

DCAF8
DDB1- and CUL4-associated factor 8

1

6

High-throughput

0.515

High

231727

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.515

High

231735

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

5

High-throughput

0.515

High

231739

RHPN1
Rhophilin-1

1

3

High-throughput

0.515

High

231741

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

1

1

High-throughput

0.515

High

231747

MYL11
Myosin regulatory light chain 11

1

4

High-throughput

0.515

High

231755

DPYL5
Dihydropyrimidinase-related protein 5

1

10

High-throughput

0.515

High

231760

SKI8
Superkiller complex protein 8

1

7

High-throughput

0.515

High

231765

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

3

High-throughput

0.515

High

231774

APC11
Anaphase-promoting complex subunit 11

1

7

High-throughput

0.515

High

231783

CSN3
COP9 signalosome complex subunit 3

1

7

High-throughput

0.515

High

231675

TNNI3
Troponin I, cardiac muscle

1

0

High-throughput

0.493

High

231724

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.493

High

231767

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.493

High

231782

ING4
Inhibitor of growth protein 4

1

0

High-throughput

0.493

High

231676

ACM3
Muscarinic acetylcholine receptor M3

1

1

High-throughput

0.489

High

231677

GRAH
Granzyme H

1

3

High-throughput

0.489

High

231681

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.489

High

231683

SSRB
Translocon-associated protein subunit beta

1

1

High-throughput

0.489

High

231707

INF2
Inverted formin-2

1

5

High-throughput

0.489

High

231726

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

231729

TSYL6
Testis-specific Y-encoded-like protein 6

1

2

High-throughput

0.489

High

231740

HUMMR
Protein MGARP

1

1

High-throughput

0.489

High

231742

NPRL2
GATOR1 complex protein NPRL2

1

2

High-throughput

0.489

High

231744

HPSE2
Inactive heparanase-2

1

1

High-throughput

0.489

High

231754

NPAS1
Neuronal PAS domain-containing protein 1

1

3

High-throughput

0.489

High

231787

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

231663

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

231667

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.479

High

231673

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

231674

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

8

High-throughput

0.479

High

231680

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.479

High

231687

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

231688

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

7

High-throughput

0.479

High

231691

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

231694

ACTC
Actin, alpha cardiac muscle 1

1

4

High-throughput

0.479

High

231696

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

231697

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

7

High-throughput

0.479

High

231700

CUL3
Cullin-3

1

12

High-throughput

0.479

High

231704

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

231705

EEA1
Early endosome antigen 1

1

7

High-throughput

0.479

High

231708

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

231709

LARP7
La-related protein 7

1

8

High-throughput

0.479

High

231718

SYNE3
Nesprin-3

1

5

High-throughput

0.479

High

231734

LNX1
E3 ubiquitin-protein ligase LNX

1

2

Small-scale

0.479

High

231745

AKAP1
A-kinase anchor protein 1, mitochondrial

1

6

High-throughput

0.479

High

231762

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

231764

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

231766

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.479

High

231769

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

231770

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

3

High-throughput

0.479

High

231781

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

231784

FIS1
Mitochondrial fission 1 protein

1

2

High-throughput

0.479

High

231692

KLF3
Krueppel-like factor 3

1

2

High-throughput

0.470

High

231698

SERC3
Serine incorporator 3

1

1

High-throughput

0.470

High

231714

LHX8
LIM/homeobox protein Lhx8

1

1

High-throughput

0.470

High

231721

Q86V28
AP-1 complex subunit gamma

1

8

High-throughput

0.470

High

231725

KT222
Keratin-like protein KRT222

1

9

High-throughput

0.470

High

231730

ZN366
Zinc finger protein 366

1

1

High-throughput

0.470

High

231737

PLPR1
Phospholipid phosphatase-related protein type 1

1

1

High-throughput

0.470

High

231743

TB22A
TBC1 domain family member 22A

1

5

High-throughput

0.470

High

231759

SEM4C
Semaphorin-4C

1

2

High-throughput

0.470

High

231768

SEM4G
Semaphorin-4G

1

1

High-throughput

0.470

High

231771

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

High-throughput

0.470

High

231778

ZN180
Zinc finger protein 180

1

1

High-throughput

0.470

High

231779

STML2
Stomatin-like protein 2, mitochondrial

1

3

High-throughput

0.470

High

231731

DTWD2
tRNA-uridine aminocarboxypropyltransferase 2

1

0

High-throughput

0.458

High

231753

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

231678

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.445

High

231713

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.445

High

124161

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.437

High

231685

TSP3
Thrombospondin-3

1

2

High-throughput

0.437

High

231717

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

231723

MIRO2
Mitochondrial Rho GTPase 2

1

14

High-throughput

0.437

High

231772

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

231773

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

2

High-throughput

0.437

High

231775

MTCH1
Mitochondrial carrier homolog 1

1

5

High-throughput

0.437

High

231786

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.437

High

231671

CB27B
Putative uncharacterized protein CDRT15P3

1

1

High-throughput

0.407

High

231719

PKHG7
Pleckstrin homology domain-containing family G member 7

1

3

High-throughput

0.407

High

231776

SL9A2
Sodium/hydrogen exchanger 2

1

1

High-throughput

0.407

High

231690

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

231711

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

231715

ISM2
Isthmin-2

1

0

High-throughput

0.279

Low

231728

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low

231746

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

231750

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

231665

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.268

Low

231716

SPAT8
Spermatogenesis-associated protein 8

1

0

High-throughput

0.268

Low

231732

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

0

High-throughput

0.268

Low

231749

TCAL4
Transcription elongation factor A protein-like 4

1

0

High-throughput

0.268

Low

231752

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025