Interactor 1: HCFC1 (P51610)
Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]
Gene: HCFC1

Interactor 2: GABPA (Q06546)
GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60)
Gene: GABPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.560

The method score is based on:

Property Details
Experiments 10675337
Identification Methods two hybrid, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 2035
Hs

1 454
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024