Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 11259596, 18524972, 14625308, 11397809, 19166926, 16951688, 16024789, 15647277, 11751856, 12054681, 10383454
Identification Methods two hybrid, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, in-gel kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, Pkinase~Pkinase
Common GO terms GO:0001959 - regulation of cytokine-mediated signaling pathway
GO:0002224 - toll-like receptor signaling pathway
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 40 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024