Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.976 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11259596, 18524972, 14625308, 11397809, 19166926, 16951688, 16024789, 15647277, 11751856, 12054681, 10383454 |
Identification Methods | two hybrid, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, in-gel kinase assay |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Death~Death, Pkinase~Pkinase |
Common GO terms | GO:0001959 - regulation of cytokine-mediated signaling pathway GO:0002224 - toll-like receptor signaling pathway GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity and 40 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024