Protein: SCS2
Vesicle-associated membrane protein-associated protein SCS2 (VAMP-associated protein SCS2) (Choline sensitivity suppressor protein 2) (VAP homolog 1)

Gene: SCS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 139
UniProt ID: P40075

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0005635 - nuclear envelope
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767936

SCS2
Vesicle-associated membrane protein-associated protein SCS2

2

8

Small-scale

0.744

High

728872

OSH1
Oxysterol-binding protein homolog 1

6

20

Small-scale

0.734

High

602477

OPI1
Transcriptional repressor OPI1

6

0

Small-scale

0.702

High

767991

OSH2
Oxysterol-binding protein homolog 2

4

20

Small-scale

0.700

High

767961

NUM1
Nuclear migration protein NUM1

4

0

High-throughput

0.676

High

762125

YM11
Uncharacterized protein YMR124W

3

0

Small-scale

0.659

High

753068

OSH3
Oxysterol-binding protein homolog 3

3

20

Small-scale

0.658

High

767956

PIL1
Sphingolipid long chain base-responsive protein PIL1

3

1

High-throughput

0.657

High

543826

HSC82
ATP-dependent molecular chaperone HSC82

3

2

High-throughput

0.633

High

366368

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.584

High

728036

YET1
Endoplasmic reticulum transmembrane protein 1

2

5

Small-scale

0.584

High

767975

RTN1
Reticulon-like protein 1

2

8

Small-scale

0.584

High

767977

PEX30
Peroxisomal membrane protein PEX30

2

1

Small-scale

0.584

High

767981

SHS1
Seventh homolog of septin 1

1

0

High-throughput

0.564

High

741335

STT4
Phosphatidylinositol 4-kinase STT4

2

0

High-throughput

0.563

High

751369

FKS1
1,3-beta-glucan synthase component FKS1

2

0

High-throughput

0.563

High

747351

PHO88
SRP-independent targeting protein 3

2

0

Small-scale

0.559

High

767995

ATG40
Autophagy-related protein 40

2

0

Small-scale

0.559

High

767954

CCH1
Calcium-channel protein CCH1

1

1

Small-scale

0.552

High

491369

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.552

High

494086

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

511489

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

563913

FCY2
Purine-cytosine permease FCY2

1

0

High-throughput

0.518

High

767982

NBA1
Protein NBA1

1

0

High-throughput

0.513

High

556079

VATB
V-type proton ATPase subunit B

2

1

High-throughput

0.504

High

767962

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

4

High-throughput

0.501

High

767966

SKY1
Serine/threonine-protein kinase SKY1

1

3

High-throughput

0.489

High

767973

ERB1
Ribosome biogenesis protein ERB1

1

1

High-throughput

0.489

High

605847

SEC22
Protein transport protein SEC22

1

5

Small-scale

0.481

High

699500

SSO1
Protein SSO1

1

20

Small-scale

0.481

High

495834

CP51
Lanosterol 14-alpha demethylase CYP51

1

4

Small-scale

0.479

High

520266

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

520344

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

541724

SEC63
Protein translocation protein SEC63

1

7

Small-scale

0.479

High

596982

ACO1
Acyl-CoA desaturase 1

1

1

Small-scale

0.479

High

634316

EMC1
ER membrane protein complex subunit 1

1

2

Small-scale

0.479

High

679912

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

1

Small-scale

0.479

High

689095

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

Small-scale

0.479

High

698418

EMP24
Endosomal protein P24B

1

8

Small-scale

0.479

High

707424

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

3

Small-scale

0.479

High

707490

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

1

Small-scale

0.479

High

745680

NU170
Nucleoporin NUP170

1

2

High-throughput

0.479

High

753825

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

759057

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

2

Small-scale

0.479

High

767943

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

Small-scale

0.479

High

767950

STE24
CAAX prenyl protease 1

1

2

Small-scale

0.479

High

767959

TMEDA
Endoplasmic reticulum vesicle protein 25

1

9

Small-scale

0.479

High

767964

PEX29
Peroxisomal membrane protein PEX29

1

1

Small-scale

0.479

High

767965

TCB3
Tricalbin-3

1

6

Small-scale

0.479

High

767970

GPI17
GPI transamidase component GPI17

1

2

Small-scale

0.479

High

767972

MYO5
Myosin-5

1

2

Small-scale

0.479

High

767976

ERP1
Protein ERP1

1

7

Small-scale

0.479

High

767980

YET3
Endoplasmic reticulum transmembrane protein 3

1

5

Small-scale

0.479

High

767989

YOP1
Protein YOP1

1

5

Small-scale

0.479

High

767990

RTN2
Reticulon-like protein 2

1

9

Small-scale

0.479

High

767992

TCB1
Tricalbin-1

1

7

Small-scale

0.479

High

767993

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

3

Small-scale

0.479

High

767937

PEA2
Protein PEA2

1

0

Small-scale

0.460

High

767940

SEC9
Protein transport protein SEC9

1

0

Small-scale

0.460

High

767955

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

425205

CARP
Saccharopepsin

1

0

Small-scale

0.458

High

534395

DPM1
Dolichol-phosphate mannosyltransferase

1

0

Small-scale

0.458

High

669532

ERG9
Squalene synthase ERG9

1

0

Small-scale

0.458

High

688573

ERG2
C-8 sterol isomerase ERG2

1

0

Small-scale

0.458

High

701452

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

732296

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

747068

IST2
Increased sodium tolerance protein 2

1

0

Small-scale

0.458

High

756014

NSG1
Protein NSG1

1

0

High-throughput

0.458

High

765997

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

Small-scale

0.458

High

767947

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

767974

GSF2
Glucose-signaling factor 2

1

0

Small-scale

0.458

High

767994

SEY1
Protein SEY1

1

0

Small-scale

0.458

High

767996

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

334484

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.445

High

334707

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.445

High

636639

CDC48
Cell division control protein 48

1

6

High-throughput

0.445

High

767938

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

767979

VPS74
Vacuolar protein sorting-associated protein 74

1

2

High-throughput

0.445

High

767987

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.445

High

767949

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.438

High

619473

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.437

High

635707

TAH1
TPR repeat-containing protein associated with Hsp90

1

1

Small-scale

0.437

High

662353

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

663873

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

680746

HS104
Heat shock protein 104

1

1

High-throughput

0.437

High

691060

HOG1
Mitogen-activated protein kinase HOG1

1

2

High-throughput

0.437

High

762240

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

767945

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

767951

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

767958

ORC1
Origin recognition complex subunit 1

1

5

High-throughput

0.437

High

767971

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.437

High

333806

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

340153

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

342937

ENO2
Enolase 2

1

0

High-throughput

0.426

High

710378

EDE1
EH domain-containing and endocytosis protein 1

1

0

High-throughput

0.426

High

767967

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.426

High

767957

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.417

High

360896

TBB
Tubulin beta chain

1

3

High-throughput

0.407

High

578540

SEC18
Vesicular-fusion protein SEC18

1

6

High-throughput

0.407

High

633260

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.407

High

657074

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.407

High

660915

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

1

High-throughput

0.407

High

713230

TSA1
Peroxiredoxin TSA1

1

2

High-throughput

0.407

High

767942

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.407

High

767953

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.407

High

767960

ACT
Actin

1

1

High-throughput

0.407

High

756935

RPN10
26S proteasome regulatory subunit RPN10

3

0

High-throughput

0.335

High

767946

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

767984

YP272
Uncharacterized protein YPL272C

1

0

Small-scale

0.282

High

756740

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.279

Low

767642

IMB4
Importin subunit beta-4

1

0

Small-scale

0.279

Low

767941

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.269

Low

606659

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

634623

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

703638

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

730813

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

767939

VID27
Vacuolar import and degradation protein 27

1

0

High-throughput

0.249

Low

767952

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

767963

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

767968

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.249

Low

767969

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

767978

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

767983

MCA1
Metacaspase-1

1

0

High-throughput

0.249

Low

767985

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

767986

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

Small-scale

0.249

Low

343620

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.232

Low

421647

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

424543

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

580555

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

588100

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

599969

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

0

High-throughput

0.232

Low

604421

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

605438

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

696796

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.232

Low

750960

YGP1
Protein YGP1

1

0

High-throughput

0.232

Low

767944

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

767948

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

767988

RPN6
26S proteasome regulatory subunit RPN6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024