HitPredict

Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 543
+	Hs
		826576 IRAK1_HUMAN (1-712): 0: 597: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821129 IRAK1_HUMAN (1-712): 0: 597: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573180 IRAK1_HUMAN (1-712): 0: 597: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843116 IRAK1_HUMAN (1-712): 0: 597: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79