HitPredict

Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 19615732, 28292943, 34349018
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PC_rep, HEAT_2~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 324
Hs

1 953
+ Hs
+ Dm
+ Sc
+ Dm
+ Sp
+ Hs
+ At
+ At
+ Dm
+ Sp
+ At
+ Sp
+ Dm
+ Sc

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Last updated: 15 Jul 2024