Interactor 1: IL12B (P43432)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40)
Gene: IL12B
Interactor 2: IL23A (Q9EQ14)
Interleukin-23 subunit alpha (IL-23 subunit alpha) (IL-23-A) (Interleukin-23 subunit p19) (IL-23p19)
Gene: IL23A
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.730 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11114383 |
| Identification Methods | anti tag coimmunoprecipitation, affinity chromatography technology, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation |
| Interaction Type | disulfide bond, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL12p40_C~IL23 |
| Common GO terms | GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002230 - positive regulation of defense response to virus by host GO:0002827 - positive regulation of T-helper 1 type immune response GO:0005125 - cytokine activity GO:0005576 - extracellular region and 18 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
