Protein: IL12B
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)

Gene: IL12B
Organism: Homo sapiens
Interactions: 19
UniProt ID: P29460

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002230 - positive regulation of defense response to virus by host
GO:0002323 - natural killer cell activation involved in immune response
GO:0002827 - positive regulation of T-helper 1 type immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

712752

IL23A
Interleukin-23 subunit alpha

5

2

Small-scale

0.937

High

712716

IL12A
Interleukin-12 subunit alpha

4

3

Small-scale

0.890

High

712742

I12R1
Interleukin-12 receptor subunit beta-1

2

17

Small-scale

0.754

High

712740

IL12B
Interleukin-12 subunit beta

1

15

Small-scale

0.715

High

712744

TF65
Transcription factor p65

4

6

Small-scale

0.676

High

712750

I12R2
Interleukin-12 receptor subunit beta-2

1

17

Small-scale

0.618

High

712743

RELB
Transcription factor RelB

2

6

Small-scale

0.584

High

712746

EP300
Histone acetyltransferase p300

2

2

Small-scale

0.584

High

712748

IL23R
Interleukin-23 receptor

1

15

Small-scale

0.536

High

533886

IRF1
Interferon regulatory factor 1

1

8

Small-scale

0.479

High

606280

CEBPB
CCAAT/enhancer-binding protein beta

1

4

Small-scale

0.479

High

698408

CALX
Calnexin

1

4

High-throughput

0.479

High

712741

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

15

Small-scale

0.479

High

712745

REL
Proto-oncogene c-Rel

1

6

Small-scale

0.479

High

712747

IRF5
Interferon regulatory factor 5

1

8

Small-scale

0.479

High

712749

CBP
CREB-binding protein

1

2

Small-scale

0.479

High

712751

ERP44
Endoplasmic reticulum resident protein 44

1

1

Small-scale

0.479

High

464831

SP1
Transcription factor Sp1

1

0

Small-scale

0.269

Low


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Last updated: 11Aug2025