HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: TRI72 (Q6ZMU5)
Tripartite motif-containing protein 72 (Mitsugumin-53) (Mg53)
Gene: TRIM72

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	35858925
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 477
+	Hs
		1336390 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI39_HUMAN (5-476): 3.13e-140: 414: 24.51
+	Hs
		584907 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		RO52_HUMAN (2-471): 3.42e-140: 412: 25.47
+	Hs
		537142 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI27_HUMAN (3-477): 2.66e-128: 383: 26.24
+	Hs
		536760 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI27_HUMAN (3-477): 2.66e-128: 383: 26.24
+	Hs
		849406 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI11_HUMAN (7-477): 1.56e-126: 377: 25.94
+	Hs
		1204911 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI50_HUMAN (3-468): 1.39e-118: 358: 31.21
+	Hs
		849360 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI50_HUMAN (3-468): 1.39e-118: 358: 31.21
+	Hs
		135045 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI38_HUMAN (2-474): 1.18e-116: 352: 24.22
+	Hs
		135012 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI38_HUMAN (2-474): 1.18e-116: 352: 24.22
+	Hs
		849366 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI22_HUMAN (7-473): 3.75e-114: 347: 22.65
+	Hs
		1377469 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI17_HUMAN (6-462): 4.83e-112: 341: 26.12
+	Hs
		1318719 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM5_HUMAN (2-473): 1.45e-111: 340: 22.09
+	Hs
		1313765 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI62_HUMAN (7-469): 1.44e-111: 339: 25.11
+	Hs
		849358 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI69_HUMAN (3-473): 6.1e-112: 341: 25.42
+	Hs
		849429 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI62_HUMAN (7-469): 1.44e-111: 339: 25.11
+	Hs
		1354526 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI10_HUMAN (2-460): 8.85e-108: 330: 22.92
+	Hs
		1285831 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI43_HUMAN (8-456): 1.35e-101: 313: 21.66
+	Hs
		1357712 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI35_HUMAN (2-471): 4.16e-101: 313: 23.25
+	Hs
		849399 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI43_HUMAN (8-456): 1.35e-101: 313: 21.66
+	Hs
		849384 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI41_HUMAN (2-42): 1.13e-09: 62.6: 36.59