HitPredict

Interactor 1: CCR3 (P51677)
C-C chemokine receptor type 3 (C C CKR3) (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR 3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193)
Gene: CCR3

Interactor 2: CCL13 (Q99616)
C-C motif chemokine 13 (CK-beta-10) (Monocyte chemoattractant protein 4) (Monocyte chemotactic protein 4) (MCP-4) (NCC-1) (Small-inducible cytokine A13) [Cleaved into: C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain]
Gene: CCL13

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	10733106
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 98
+	Mm
		500591 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL3_MOUSE (1-93): 1.18e-35: 118: 43.01
+	Hs
		561728 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CL3L1_HUMAN (1-93): 1.3e-36: 120: 41.94
+	Hs
		526560 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL4_HUMAN (1-92): 6.96e-36: 118: 39.13
+	Hs
		686667 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL14_HUMAN (1-92): 5.26e-34: 114: 35.48
+	Hs
		486230 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL3_HUMAN (1-93): 1.45e-33: 113: 38.71
+	Mm
		534669 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL4_MOUSE (1-92): 7.96e-31: 106: 39.13
+	Hs
		686635 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL8_HUMAN (1-97): 3.41e-32: 109: 62.25
+	Hs
		528201 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL2_HUMAN (1-98): 6.78e-31: 106: 64.65
+	Hs
		686636 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL7_HUMAN (17-97): 1.05e-30: 105: 60.98
+	Hs
		686626 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL23_HUMAN (1-95): 1.87e-28: 100: 28.70
+	Hs
		686668 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL15_HUMAN (1-90): 6.93e-28: 99.3: 31.19
+	Hs
		607526 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL1_HUMAN (1-97): 7.09e-28: 98.9: 31.96
+	Hs
		528244 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL5_HUMAN (1-91): 4.66e-27: 96.6: 31.87
+	Hs
		607528 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL1_HUMAN (1-97): 7.09e-28: 98.9: 31.96
+	Hs
		849723 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL18_HUMAN (1-93): 3.43e-27: 96.6: 34.41
+	Mm
		486212 CCR8_MOUSE (1-335): 1.93e-91: 279: 37.57		CCL1_MOUSE (1-89): 5.54e-22: 83.5: 35.56
+	Hs
		849725 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL17_HUMAN (7-90): 1.94e-25: 92.3: 30.95
+	Hs
		180158 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL16_HUMAN (1-88): 8.65e-22: 83.9: 34.07
+	Hs
		180162 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL16_HUMAN (1-88): 8.65e-22: 83.9: 34.07
+	Hs
		134312 ACKR4_HUMAN (10-343): 1e-85: 264: 30.09		CCL21_HUMAN (24-97): 1.18e-17: 73.8: 29.49