Interactor 1: CCR3 (P51678)
Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD antigen CD193)
Gene: CCR3

Interactor 2: CCR5 (P51682)
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD antigen CD195)
Gene: CCR5

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9139699
Identification Methods competition binding
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0006954 - inflammatory response
GO:0006955 - immune response
GO:0007204 - positive regulation of cytosolic calcium ion concentration
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 359
Mm

1 354
+ Hs
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+ Rn
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+ Hs

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Last updated: 15 Jul 2024