HitPredict

Interactor 1: CCR8 (P51685)
C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198)
Gene: CCR8

Interactor 2: CCL17 (Q92583)
C-C motif chemokine 17 (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine)
Gene: CCL17

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10910894
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 94
+	Hs
		849619 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL13_HUMAN (6-94): 5.69e-34: 113: 29.21
+	Hs
		526564 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL4_HUMAN (4-91): 1.63e-33: 112: 27.27
+	Hs
		561732 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CL3L1_HUMAN (3-92): 3.23e-32: 109: 27.17
+	Hs
		849614 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL7_HUMAN (16-94): 7.08e-31: 106: 30.00
+	Hs
		849616 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL14_HUMAN (1-91): 5.9e-31: 106: 29.67
+	Hs
		486237 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL3_HUMAN (3-92): 7.79e-31: 105: 26.37
+	Hs
		528210 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL2_HUMAN (15-94): 6.73e-29: 101: 23.46
+	Hs
		118813 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL24_HUMAN (1-93): 3.43e-28: 100: 24.47
+	Hs
		849504 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL11_HUMAN (16-94): 4.16e-27: 96.6: 30.00
+	Hs
		849613 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL18_HUMAN (7-92): 2.31e-26: 94.6: 27.91
+	Hs
		528252 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL5_HUMAN (14-90): 3.37e-25: 91.6: 25.97
+	Hs
		849620 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL26_HUMAN (22-93): 3.75e-25: 91.6: 27.78
+	Hs
		849617 CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64		CCL15_HUMAN (26-89): 1.77e-23: 87.7: 29.69
+	Hs
		134356 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL4_HUMAN (4-91): 1.63e-33: 112: 27.27
+	Hs
		825305 CX3C1_HUMAN (5-350): 5.91e-86: 265: 38.91		X3CL1_HUMAN (1-92): 1.76e-25: 98.9: 28.42
+	Hs
		134373 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL8_HUMAN (15-94): 8.16e-31: 106: 23.46
+	Hs
		134354 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL3_HUMAN (3-92): 7.79e-31: 105: 26.37
+	Hs
		134357 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL2_HUMAN (15-94): 6.73e-29: 101: 23.46
+	Hs
		134369 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL11_HUMAN (16-94): 4.16e-27: 96.6: 30.00
+	Hs
		134358 ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33		CCL5_HUMAN (14-90): 3.37e-25: 91.6: 25.97