HitPredict

Interactor 1: BMX (P51813)
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)
Gene: BMX

Interactor 2: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 11331870
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr, FERM_M~PK_Tyr_Ser-Thr, FERM_N_2~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024