HitPredict

Interactor 1: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21907836
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 240 Hs			1 126
+	Hs
		850932 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		241483 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41
+	Hs
		850890 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		855491 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62
+	Hs
		855488 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		855445 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00
+	Hs
		855449 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1087155 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		918404 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1087480 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		707787 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918769 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1087385 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		266023 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		266045 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		265986 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		707738 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918663 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		331825 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		331768 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21