Protein: KI3L1
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)

Gene: KI3L1, KIR3DL1
Organism: Homo sapiens
Interactions: 22
UniProt ID: P43629

Gene Ontology (top 5):
GO:0002764 - immune response-regulating signaling pathway
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0030109 - HLA-B specific inhibitory MHC class I receptor activity
GO:0042267 - natural killer cell mediated cytotoxicity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850863

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

3

14

High-throughput

0.861

High

719701

HLAF
HLA class I histocompatibility antigen, alpha chain F

2

20

Small-scale

0.789

High

850796

KI2L2
Killer cell immunoglobulin-like receptor 2DL2

2

15

High-throughput

0.754

High

850769

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

14

High-throughput

0.691

High

379934

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

20

Small-scale

0.618

High

607353

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

20

Small-scale

0.618

High

850864

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

20

Small-scale

0.618

High

850872

F1142
Protein FAM114A2

3

4

High-throughput

0.604

High

850868

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

1

18

High-throughput

0.575

High

335543

BMP10
Bone morphogenetic protein 10

2

1

High-throughput

0.553

High

850867

PCDH1
Protocadherin-1

1

4

High-throughput

0.515

High

850870

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

2

High-throughput

0.515

High

658575

KS6B1
Ribosomal protein S6 kinase beta-1

1

10

High-throughput

0.494

High

231302

EFNA2
Ephrin-A2

1

2

Small-scale

0.479

High

711057

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

Small-scale

0.479

High

850865

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.479

High

850869

TAFA2
Chemokine-like protein TAFA-2

1

3

Small-scale

0.457

High

593045

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.437

High

617084

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

2

Small-scale

0.437

High

850866

GABPA
GA-binding protein alpha chain

1

2

Small-scale

0.437

High

850871

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.316

High

675400

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025