HitPredict

Interactor 1: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 21907836
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 240 Hs			1 183
+	Mm
		1265741 GLYR1_MOUSE (6-228): 1.63e-44: 158: 23.40		Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027327 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027243 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		266006 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		331801 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027303 DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1143040 GLYR1_MOUSE (6-228): 1.63e-44: 158: 23.40		CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89
+	Mm
		949958 GLYR1_MOUSE (6-228): 1.63e-44: 158: 23.40		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		1027088 HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1317731 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		V9HWG0_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		800517 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		265992 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		949878 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		800543 DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949904 DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Dm
		399008 ZMYD8_DROME (2-240): 1.84e-37: 140: 17.32		HP1_DROME (9-180): 2.12e-45: 150: 38.73
+	Hs
		949825 HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		203801 DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Mm
		291745 DNM3B_MOUSE (8-211): 2.22e-38: 143: 15.57		CBX2_MOUSE (20-117): 6.27e-26: 104: 27.00