HitPredict

Interactor 1: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Interactor 2: MARH5 (Q9NX47)
E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5)
Gene: MARCHF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16936636
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 278
+	Hs
		919880 UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		849461 UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		1282354 UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		895930 UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		896552 UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Dm
		715100 UBE2N_DROME (45-192): 4.17e-69: 209: 45.27		Q9VB61_DROME (10-278): 9.68e-143: 404: 39.71