HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: PEAK1 (Q9H792)
Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
Gene: PEAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005829 - cytosol GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Hs			1 1746
+	Hs
		901244 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		1269226 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		900910 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		436511 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		925619 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		914361 RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		892599 RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		545621 RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		951343 RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		915979 RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		120644 RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		568611 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		436148 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		681775 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		AKT1_HUMAN (1362-1695): 4.43e-91: 307: 15.07
+	Hs
		568619 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		900861 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Hs
		1315495 RAB1B_HUMAN (2-224): 3.11e-79: 237: 19.64		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Ce
		136800 RHO1_CAEEL (9-184): 5.42e-82: 244: 50.00		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80
+	Ce
		136793 RAC1_CAEEL (8-194): 1.45e-77: 233: 42.78		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80
+	Ce
		104464 G5EBV3_CAEEL (1-194): 1.76e-76: 230: 37.11		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80