Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: OTU1 (Q5VVQ6)
Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (DUBA-8) (HIV-1-induced protease 7) (HIN-7) (HsHIN7) (OTU domain-containing protein 2)
Gene: YOD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 37667382
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0071108 - protein K48-linked deubiquitination
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 858
Hs

1 348
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025