HitPredict

Interactor 1: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

Property	Details
Experiments	26186194, 26496610, 28514442, 24981860, 33961781, 35271311, 17643375, 15282305
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 172
+	Sp
		145816 RPB11_SCHPO (1-117): 1.68e-40: 132: 45.30		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		710008 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Hs
		854499 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Hs
		484502 RPAC2_HUMAN (12-116): 3.57e-40: 131: 30.56		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Sc
		655601 RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33		RPC8_YEAST (1-158): 1.07e-49: 160: 19.39