HitPredict

Interactor 1: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Interactor 2: TF2B (Q00403)
Transcription initiation factor IIB (EC 2.3.1.48) (General transcription factor TFIIB) (S300-II)
Gene: GTF2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35271311, 17643375, 15282305
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006366 - transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 316
+	Sc
		662200 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		TF2B_YEAST (13-314): 1.08e-103: 308: 33.54
+	Hs
		484465 RPAC2_HUMAN (12-116): 3.57e-40: 131: 30.56		TF3B_HUMAN (15-313): 7.73e-96: 299: 21.19
+	Sc
		655587 RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33		TF2B_YEAST (13-314): 1.08e-103: 308: 33.54
+	Sc
		663862 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		TF3B_YEAST (15-306): 9.45e-89: 278: 21.41
+	Sc
		655588 RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33		TF3B_YEAST (15-306): 9.45e-89: 278: 21.41