HitPredict

Interactor 1: UBCD2 (P52485)
Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: Ubc2

Interactor 2: Q8IR26 (Q8IR26)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: sordd2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Dm			1 283
+	Dm
		854578 UBCD2_DROME (1-232): 2.16e-92: 272: 100.00		Q9VXP1_DROME (1-274): 4.03e-80: 245: 91.27
+	Dm
		1215059 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q8IR26_DROME (1-283): 1.12e-84: 256: 100.00
+	Dm
		1337333 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q9VXP1_DROME (1-274): 4.03e-80: 245: 91.27
+	Hs
		1292368 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RN185_HUMAN (92-275): 1.31e-51: 169: 48.39
+	Hs
		919826 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN185_HUMAN (92-275): 1.31e-51: 169: 48.39
+	Hs
		1292341 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		RN185_HUMAN (92-275): 1.31e-51: 169: 48.39
+	Hs
		1307272 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RNF5_HUMAN (103-257): 1.34e-47: 158: 50.97
+	Hs
		919838 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RNF5_HUMAN (103-257): 1.34e-47: 158: 50.97
+	Hs
		1349425 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		BFAR_HUMAN (92-283): 7.21e-32: 124: 16.06
+	Hs
		919883 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		BFAR_HUMAN (92-283): 7.21e-32: 124: 16.06
+	Hs
		919822 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI11_HUMAN (111-216): 8.49e-30: 118: 24.53
+	Hs
		262167 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRIM3_HUMAN (106-260): 5.51e-27: 112: 17.79
+	Hs
		262201 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		TRIM3_HUMAN (106-260): 5.51e-27: 112: 17.79
+	Hs
		919712 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI26_HUMAN (118-265): 7.51e-27: 111: 20.38
+	Hs
		262192 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		TRIM3_HUMAN (106-260): 5.51e-27: 112: 17.79
+	Hs
		919828 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN170_HUMAN (87-277): 1.24e-25: 103: 18.69
+	Hs
		919794 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		COP1_HUMAN (114-178): 3.02e-17: 83.4: 32.31
+	Hs
		1246146 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		COP1_HUMAN (114-178): 3.02e-17: 83.4: 32.31
+	Hs
		749339 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		BRCA1_HUMAN (124-174): 4.47e-16: 80.3: 35.29
+	Hs
		749782 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		BRCA1_HUMAN (124-174): 4.47e-16: 80.3: 35.29