HitPredict

Interactor 1: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045202 - synapse and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 415 Hs			1 305
+	Hs
		516358 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609772 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609726 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		201658 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56
+	Hs
		516495 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		201661 HNRH2_HUMAN (1-413): 9.35e-67: 220: 72.40		MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56
+	Hs
		516339 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		682930 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		MSI2H_HUMAN (5-303): 2.55e-56: 186: 32.11
+	Hs
		682790 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA0_HUMAN (1-268): 2.87e-55: 183: 100.00
+	Hs
		516689 PABP3_HUMAN (1-409): 1.76e-72: 240: 12.13		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		453107 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		516424 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		453231 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		516511 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161948 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		453174 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		682738 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		855056 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		682807 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161970 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91