Interactor 1: TF2AA (P52655)
Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)]
Gene: GTF2A1

Interactor 2: T2AG (P52657)
Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma)
Gene: GTF2A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25416956, 26186194, 28514442, 17643375, 32296183, 33961781, 8626665, unassigned1304, 7724559, 31515488
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TFIIA~TFIIA_gamma_C, TFIIA~TFIIA_gamma_N
Common GO terms GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0005672 - transcription factor TFIIA complex
and 8 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 376
Hs

1 109
+ At
+ At
+ Dm
+ Dm
+ Sc

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Last updated: 15 Jul 2024